Product Name :
Procyanidin C1
Description:
Procyanidin C1 is a natural polyphenol, causes DNA damage, cell cycle arrest, and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells.
CAS:
37064-30-5
Molecular Weight:
866.77
Formula:
C45H38O18
Chemical Name:
(2R, 3R, 4S)-2-(3, 4-dihydroxyphenyl)-8-[(2R, 3R, 4R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-4-yl]-4-[(2R, 3R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-8-yl]-3, 4-dihydro-2H-1-benzopyran-3, 5, 7-triol
Smiles :
OC1C=C2O[C@@H]([C@H](O)[C@@H](C3=C4O[C@@H]([C@H](O)[C@H](C4=C(O)C=C3O)C3=C4O[C@@H]([C@H](O)CC4=C(O)C=C3O)C3=CC(O)=C(O)C=C3)C3=CC(O)=C(O)C=C3)C2=C(O)C=1)C1=CC(O)=C(O)C=C1
InChiKey:
MOJZMWJRUKIQGL-XILRTYJMSA-N
InChi :
InChI=1S/C45H38O18/c46-18-10-27(54)33-32(11-18)61-42(16-2-5-21(48)25(52)8-16)39(59)37(33)35-29(56)14-30(57)36-38(40(60)43(63-45(35)36)17-3-6-22(49)26(53)9-17)34-28(55)13-23(50)19-12-31(58)41(62-44(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,31,37-43,46-60H,12H2/t31-,37-,38+,39-,40-,41-,42-,43-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Procyanidin C1 is a natural polyphenol, causes DNA damage, cell cycle arrest, and induces apoptosis.Pyrimethamine site Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells.Tenapanor Protocol |Product information|CAS Number: 37064-30-5|Molecular Weight: 866.PMID:32543998 77|Formula: C45H38O18|Chemical Name: (2R, 3R, 4S)-2-(3, 4-dihydroxyphenyl)-8-[(2R, 3R, 4R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-4-yl]-4-[(2R, 3R)-2-(3, 4-dihydroxyphenyl)-3, 5, 7-trihydroxy-3, 4-dihydro-2H-1-benzopyran-8-yl]-3, 4-dihydro-2H-1-benzopyran-3, 5, 7-triol|Smiles: OC1C=C2O[C@@H]([C@H](O)[C@@H](C3=C4O[C@@H]([C@H](O)[C@H](C4=C(O)C=C3O)C3=C4O[C@@H]([C@H](O)CC4=C(O)C=C3O)C3=CC(O)=C(O)C=C3)C3=CC(O)=C(O)C=C3)C2=C(O)C=1)C1=CC(O)=C(O)C=C1|InChiKey: MOJZMWJRUKIQGL-XILRTYJMSA-N|InChi: InChI=1S/C45H38O18/c46-18-10-27(54)33-32(11-18)61-42(16-2-5-21(48)25(52)8-16)39(59)37(33)35-29(56)14-30(57)36-38(40(60)43(63-45(35)36)17-3-6-22(49)26(53)9-17)34-28(55)13-23(50)19-12-31(58)41(62-44(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,31,37-43,46-60H,12H2/t31-,37-,38+,39-,40-,41-,42-,43-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (115.37 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Koteswari LL, et al. A comparative anticancer study on procyanidin C1 against receptor positive and receptor negative breast cancer. Nat Prod Res. 2019 Jan 8:1-8.Products are for research use only. Not for human use.|
