Product Name :
AZD3458
Description:
AZD3458 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively.
CAS:
2132961-46-5
Molecular Weight:
433.54
Formula:
C20H23N3O4S2
Chemical Name:
N-(5-{2-[(1S)-1-cyclopropylethyl]-7-methanesulfonyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-4-methyl-1,3-thiazol-2-yl)acetamide
Smiles :
C[C@@H](C1CC1)N1CC2=CC(=CC(=C2C1=O)S(C)(=O)=O)C1SC(NC(C)=O)=NC=1C
InChiKey:
PAQUFWFUOVDUIO-NSHDSACASA-N
InChi :
InChI=1S/C20H23N3O4S2/c1-10-18(28-20(21-10)22-12(3)24)14-7-15-9-23(11(2)13-5-6-13)19(25)17(15)16(8-14)29(4,26)27/h7-8,11,13H,5-6,9H2,1-4H3,(H,21,22,24)/t11-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tomivosertib} MedChemExpress|{Tomivosertib} MNK|{Tomivosertib} Protocol|{Tomivosertib} In stock|{Tomivosertib} custom synthesis|{Tomivosertib} Epigenetics}
Additional information:
AZD3458 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.{{Blebbistatin} MedChemExpress|{Blebbistatin} Cytoskeleton|{Blebbistatin} Purity & Documentation|{Blebbistatin} Formula|{Blebbistatin} supplier|{Blebbistatin} Epigenetic Reader Domain} 1, 5.1, Product information|CAS Number: 2132961-46-5|Molecular Weight: 433.54|Formula: C20H23N3O4S2|Chemical Name: N-(5-{2-[(1S)-1-cyclopropylethyl]-7-methanesulfonyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-4-methyl-1,3-thiazol-2-yl)acetamide|Smiles: C[C@@H](C1CC1)N1CC2=CC(=CC(=C2C1=O)S(C)(=O)=O)C1SC(NC(C)=O)=NC=1C|InChiKey: PAQUFWFUOVDUIO-NSHDSACASA-N|InChi: InChI=1S/C20H23N3O4S2/c1-10-18(28-20(21-10)22-12(3)24)14-7-15-9-23(11(2)13-5-6-13)19(25)17(15)16(8-14)29(4,26)27/h7-8,11,13H,5-6,9H2,1-4H3,(H,21,22,24)/t11-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (576.PMID:24293312 65 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|AZD3458 (Compound 15) also inhibits PI3KC2α, PI3KC2β, PI3KC2γ, and PI3KC3 with pIC50s of Products are for research use only. Not for human use.|
