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Sed and analysed in the course of the present study are readily available in the corresponding author on affordable request. E TH I CS S T A TE M E N T Ethical HIV-2 Inhibitor Biological Activity approval was obtained in the Ethical Evaluation Committee on the Chinese Centre for Disease Control and Prevention (Beijing, China) along with the Oxford Tropical Investigation Ethics Committee, University of Oxford (UK), and all participants provided written informed consent. ORCID Ling Yang https://orcid.org/0000-0001-5750-RE FE R ENC E S1. Planet Overall health Organization. Global Status Report on Alcohol and Well being. Geneva: WHO; 2018. two. Griswold MG, Fullman N, Hawley C, et al. Alcohol use and burden for 195 nations and territories, 1990016: a systematic evaluation for the international burden of illness Study 2016. The Lancet. 2018;392:10151035. 3. Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115-132. 4. Im PK, Millwood IY, Guo Y, et al. Patterns and trends of alcohol HDAC6 Inhibitor Synonyms consumption in rural and urban regions of China: findings in the China Kadoorie Biobank. BMC Public Overall health. 2019;19:217. five. IARC Functioning Group on the Evaluation of Carcinogenic Dangers to Humans. Private habits and indoor combustions. Volume one hundred E. A review of human carcinogens. IARC Monogr Eval Carcinog Risks Hum. 2012;one hundred(Pt E):1-538. six. Globe Cancer Study Fund/American Institute for Cancer Research. Diet program, Nutrition, Physical Activity and Cancer: a Worldwide Perspective. Continuous Update Project Professional Report 2018. Accessible at dietandcancerreport.org. 7. Bagnardi V, Rota M, Botteri E, et al. Alcohol consumption and sitespecific cancer danger: a extensive dose-response meta-analysis. Br J Cancer. 2015;112:580-593. eight. Saito E, Inoue M, Sawada N, et al. Influence of alcohol intake and drinking patterns on mortality from all causes and main causes of death in a Japanese population. J Epidemiol. 2018;28:140-148. 9. Cao Y, Willett WC, Rimm EB, Stampfer MJ, Giovannucci EL. Light to moderate intake of alcohol, drinking patterns, and danger of cancer: outcomes from two potential US cohort studies. BMJ. 2015;351: h4238.10. Fan Y, Yuan JM, Wang R, Gao YT, Yu MC. Alcohol, tobacco, and diet plan in relation to esophageal cancer: the Shanghai Cohort Study. Nutr Cancer. 2008;60:354-363. 11. Moy KA, Fan Y, Wang R, Gao YT, Yu MC, Yuan JM. Alcohol and tobacco use in relation to gastric cancer: a prospective study of men in Shanghai, China. Cancer Epidemiol Biomark Prev. 2010;19:22872297. 12. Shen C, Schooling CM, Chan WM, Xu L, Lee SY, Lam TH. Alcohol intake and death from cancer in a potential Chinese elderly cohort study in Hong Kong. J Epidemiol Neighborhood Health. 2013;67: 813-820. 13. Yuan JM, Ross RK, Gao YT, Henderson BE, Yu MC. Stick to up study of moderate alcohol intake and mortality amongst middle aged guys in Shanghai, China. BMJ. 1997;314:18-23. 14. Yang L, Zhou M, Sherliker P, et al. Alcohol drinking and overall and cause-specific mortality in China: nationally representative prospective study of 220,000 men with 15 years of follow-up. Int J Epidemiol. 2012;41:1101-1113. 15. Chen K, Jiang Q, Ma X, et al. Alcohol drinking and colorectal cancer: a population-based prospective cohort study in China. Eur J Epidemiol. 2005;20:149-154. 16. Pang Y, Holmes MV, Guo Y, et al. Smoking, alcohol, and diet program in relation to threat of pancreatic cancer in China: a potential study of 0.5 million people. Cancer Med. 2018;7:229-239. 17. Yu C, Guo Y, Bian Z, et al. Association of low-activity ALDH2 and alcohol consumption with risk of esoph.

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Author: Menin- MLL-menin