Results:Make use of the rendered know-how for the 3D printing of auxetic structures with metallic alloys by means of powder bed fusion for lightweight power absorption applications and for human bone implants with adapted stiffness properties; Implement material properties inside the finite element model derived in the experimental mechanical characterization of samples created by the unique 3D printing method, i.e., FDM or SLS, with specific procedure parameters, as a way to replicate irregularities and achievable anisotropy within the true built-up material; Boost the finite element model definition to contain get in touch with circumstances between and inside the auxetic unit cells, plasticity behavior, and fracture criteria; Perform experimental testing at greater impact speeds to characterize the auxetic behavior at high strain prices.Author Contributions: Conceptualization, D.P. and L.P.; methodology, D.P. and L.P.; application, D.P. and L.P.; validation, D.P., S.A., F.S., F.V., O.J. and L.P.; formal evaluation, D.P., S.A., F.S., F.V. and O.J.; investigation, D.P., S.A. and L.P.; resources, D.P., S.A., F.S., F.V., O.J. and L.P.; data curation, D.P. and S.A.; writing–original draft preparation, D.P., S.A., F.S., F.V., O.J. and L.P.; writing–review and editing, D.P. and L.P.; visualization, D.P. and S.A.; supervision, L.P.; project administration, D.P., S.A. and L.P.; funding acquisition, D.P, S.A., O.J. and L.P. All authors have read and agreed to the published version from the manuscript. Funding: This investigation was funded by the European Commission’s Horizon 2020 analysis and innovation system below the grant quantity 768775. Acknowledgments: This analysis was funded in the frame of the AMable Project by the European Commission’s Horizon 2020 research and innovation system below the Grant agreement 768775. Project website: http://www.amable.eu (accessed on 30 October 2021). Conflicts of Interest: The authors declare no conflict of interest.Appl. Sci. 2021, 11,14 of
pathogensReviewThe Flo Adhesin FamilyRonnie G. Willaert 1,two,3, , Yeseren Kayacan 1,2,3,4 and Bart Devreese 2,3,4,4Research Group Structural Biology Goralatide Technical Information Brussels (SBB), Vrije Universiteit Brussel (VUB), 1050 Brussels, Belgium; [email protected] Alliance Analysis Group VUB-UGent NanoMicrobiology (NAMI), 1050 Brussels, Belgium; [email protected] International Joint Research Group VUB-EPFL NanoBiotechnology NanoMedicine (NANO), Vrije Universiteit Brussel (VUB), 1050 Brussels, Belgium Ecole Polytechnique F ale de Lausanne, 1015 Lausanne, Switzerland Laboratory for Microbiology, Gent University (UGent), 9000 Gent, Belgium Correspondence: [email protected]; Tel.: JNJ-42253432 web 32-2629-Abstract: The first step inside the infection of fungal pathogens in humans would be the adhesion from the pathogen to host tissue cells or abiotic surfaces for example catheters and implants. Among the main players involved within this are the expressed cell wall adhesins. Right here, we critique the Flo adhesin family members and their involvement in the adhesion of these yeasts during human infections. Firstly, we redefined the Flo adhesin family members according to the domain architectures which might be present in the Flo adhesins and their functions, and setup a brand new classification of Flo adhesins. Subsequent, the structure, function, and adhesion mechanisms of your Flo adhesins whose structure has been solved are discussed in detail. Ultimately, we identified from Pfam database datamining yeasts that could express Flo adhesins and are encountered in human infections and their adhesi.
