Product Name :
Mulberrin
Description:
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
CAS:
62949-79-5
Molecular Weight:
422.47
Formula:
C25H26O6
Chemical Name:
2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-en-1-yl)-4H-chromen-4-one
Smiles :
CC(C)=CCC1C(=O)C2C(OC=1C1C=CC(O)=CC=1O)=C(CC=C(C)C)C(O)=CC=2O
InChiKey:
UWQYBLOHTQWSQD-UHFFFAOYSA-N
InChi :
InChI=1S/C25H26O6/c1-13(2)5-8-17-20(28)12-21(29)22-23(30)18(9-6-14(3)4)24(31-25(17)22)16-10-7-15(26)11-19(16)27/h5-7,10-12,26-29H,8-9H2,1-4H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.|Product information|CAS Number: 62949-79-5|Molecular Weight: 422.47|Formula: C25H26O6|Synonym:|Kuwanon C|Chemical Name: 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-en-1-yl)-4H-chromen-4-one|Smiles: CC(C)=CCC1C(=O)C2C(OC=1C1C=CC(O)=CC=1O)=C(CC=C(C)C)C(O)=CC=2O|InChiKey: UWQYBLOHTQWSQD-UHFFFAOYSA-N|InChi: InChI=1S/C25H26O6/c1-13(2)5-8-17-20(28)12-21(29)22-23(30)18(9-6-14(3)4)24(31-25(17)22)16-10-7-15(26)11-19(16)27/h5-7,10-12,26-29H,8-9H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (236.70 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.Tecarfarin medchemexpress |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Afoxolaner Autophagy |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Mulberrin is a flavone with two isopentenyl groups at positions 3 and 8.PMID:33161159 Mulberrin is a strong inhibitor of OATP2B1 with more than 80% inhibition.Mulberrin also inhibits organic anion-transporting polypeptide (OATP)-mediated uptake of Atorvastatin, Fluvastatin, and Rosuvastatin.|References:|Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54(2):293-302.Products are for research use only. Not for human use.|
