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Product Name :
Itanapraced

Description:
Itanapraced (CHF5074) is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM, respectively.

CAS:
749269-83-8

Molecular Weight:
325.16

Formula:
C16H11Cl2FO2

Chemical Name:
1-3′,4′-dichloro-2-fluoro-[1,1′-biphenyl]-4-ylcyclopropane-1-carboxylic acid

Smiles :
OC(=O)C1(CC1)C1C=C(F)C(=CC=1)C1C=C(Cl)C(Cl)=CC=1

InChiKey:
LIYLTQQDABRNRX-UHFFFAOYSA-N

InChi :
InChI=1S/C16H11Cl2FO2/c17-12-4-1-9(7-13(12)18)11-3-2-10(8-14(11)19)16(5-6-16)15(20)21/h1-4,7-8H,5-6H2,(H,20,21)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Eltrombopag Immunology/Inflammation

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Formononetin Apoptosis

Additional information:
Itanapraced (CHF5074) is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.PMID:33172306 6 and 18.4 μM, respectively.|Product information|CAS Number: 749269-83-8|Molecular Weight: 325.16|Formula: C16H11Cl2FO2|Chemical Name: 1-3′,4′-dichloro-2-fluoro-[1,1′-biphenyl]-4-ylcyclopropane-1-carboxylic acid|Smiles: OC(=O)C1(CC1)C1C=C(F)C(=CC=1)C1C=C(Cl)C(Cl)=CC=1|InChiKey: LIYLTQQDABRNRX-UHFFFAOYSA-N|InChi: InChI=1S/C16H11Cl2FO2/c17-12-4-1-9(7-13(12)18)11-3-2-10(8-14(11)19)16(5-6-16)15(20)21/h1-4,7-8H,5-6H2,(H,20,21)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (307.54 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Author: Menin- MLL-menin