Product Name :
Progesterone
Description:
AKT inhibitor VIII, also known as AKTi-1/2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway. AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells. AKT inhibitor VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase.
CAS:
57-83-0
Molecular Weight:
314.46
Formula:
C21H30O2
Chemical Name:
(1S,3aS,3bS,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Smiles :
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChiKey:
RJKFOVLPORLFTN-LEKSSAKUSA-N
InChi :
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Doxorubicin} MedChemExpress|{Doxorubicin} Epigenetics|{Doxorubicin} Purity & Documentation|{Doxorubicin} In Vivo|{Doxorubicin} supplier|{Doxorubicin} Epigenetic Reader Domain}
Additional information:
AKT inhibitor VIII, also known as AKTi-1/2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway.{{Penfluridol} web|{Penfluridol} Inducer|{Penfluridol} Epigenetics|{Penfluridol} Biological Activity|{Penfluridol} Data Sheet|{Penfluridol} custom synthesis} AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells.PMID:23746961 AKT inhibitor VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase.|Product information|CAS Number: 57-83-0|Molecular Weight: 314.46|Formula: C21H30O2|Chemical Name: (1S,3aS,3bS,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one|Smiles: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C|InChiKey: RJKFOVLPORLFTN-LEKSSAKUSA-N|InChi: InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
