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Product Name :
GNE0877

Description:
GNE-0877 is a highly potent and selective LRRK2 inhibitor. Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in the neuroscience research community because it is one of the most compelling targets for a potential disease-modifying Parkinson’s disease therapy.

CAS:
1374828-69-9

Molecular Weight:
339.32

Formula:
C14H16F3N7

Chemical Name:
2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile

Smiles :
CC(C)(C#N)N1C=C(NC2=NC(NC)=C(C=N2)C(F)(F)F)C(C)=N1

InChiKey:
ZPPUMAMZIMPJGP-UHFFFAOYSA-N

InChi :
InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Carnosol} medchemexpress|{Carnosol} MAPK/ERK Pathway|{Carnosol} Biological Activity|{Carnosol} Purity|{Carnosol} custom synthesis|{Carnosol} Autophagy}

Additional information:
GNE-0877 is a highly potent and selective LRRK2 inhibitor.{{Liraglutide} MedChemExpress|{Liraglutide} GPCR/G Protein|{Liraglutide} Purity & Documentation|{Liraglutide} Purity|{Liraglutide} supplier|{Liraglutide} Autophagy} Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in the neuroscience research community because it is one of the most compelling targets for a potential disease-modifying Parkinson’s disease therapy.|Product information|CAS Number: 1374828-69-9|Molecular Weight: 339.32|Formula: C14H16F3N7|Chemical Name: 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile|Smiles: CC(C)(C#N)N1C=C(NC2=NC(NC)=C(C=N2)C(F)(F)F)C(C)=N1|InChiKey: ZPPUMAMZIMPJGP-UHFFFAOYSA-N|InChi: InChI=1S/C14H16F3N7/c1-8-10(6-24(23-8)13(2,3)7-18)21-12-20-5-9(14(15,16)17)11(19-4)22-12/h5-6H,1-4H3,(H2,19,20,21,22)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23833812 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Author: Menin- MLL-menin