Product Name :
Adrenochrome
Description:
Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research.
CAS:
54-06-8
Molecular Weight:
179.17
Formula:
C9H9NO3
Chemical Name:
3-hydroxy-1-methyl-2,3,5,6-tetrahydro-1H-indole-5,6-dione
Smiles :
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChiKey:
RPHLQSHHTJORHI-UHFFFAOYSA-N
InChi :
InChI=1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Isorhamnetin} MedChemExpress|{Isorhamnetin} PI3K/Akt/mTOR|{Isorhamnetin} Biological Activity|{Isorhamnetin} In stock|{Isorhamnetin} custom synthesis|{Isorhamnetin} Epigenetic Reader Domain}
Additional information:
Adrenochrome (Adraxone) is an oxidation product of Epinephrine.{{Recombinant Murine Interleukin-6} site|{Recombinant Murine Interleukin-6} Purity & Documentation|{Recombinant Murine Interleukin-6} References|{Recombinant Murine Interleukin-6} custom synthesis|{Recombinant Murine Interleukin-6} Cancer} Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research.PMID:23892746 |Product information|CAS Number: 54-06-8|Molecular Weight: 179.17|Formula: C9H9NO3|Chemical Name: 3-hydroxy-1-methyl-2,3,5,6-tetrahydro-1H-indole-5,6-dione|Smiles: CN1CC(O)C2=CC(=O)C(=O)C=C12|InChiKey: RPHLQSHHTJORHI-UHFFFAOYSA-N|InChi: InChI=1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (558.13 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Adrenochrome decreases microsomal calcium binding, calcium uptake and Ca2+-stimulated Mg2+-dependent ATPase activities. The inhibitory effect of Adrenochrome on microsomal calcium uptake activity of the isolated membrane is independent of pH (6.0-8.0), calcium concentrations (10-200 μM), protein concentration (0.02-0.10 mg/mL), temperature (25-37 degrees C) and incubation time (2-30 min).|In Vivo:|In isolated rat hearts, concentrations of Adrenochrome from 1 to 1000 ng/mL increases coronary pressure in a dose- and time-dependent manner. Furthermore, the degree of constriction by Adrenochrome is dependent on the CaCl2 concentration in the perfusion medium.|Products are for research use only. Not for human use.|
