Product Name :
Methyl-Hesperidin
Description:
Methyl-Hesperidin is a vasodilating agent[1].
CAS:
11013-97-1
Molecular Weight:
624.59
Formula:
C29H36O15
Chemical Name:
(2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one
Smiles :
C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=CC(O)=C4C(=O)C[C@H](OC4=C3)C3=CC(OC)=C(C=C3)OC)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
InChiKey:
GUMSHIGGVOJLBP-SLRPQMTOSA-N
InChi :
InChI=1S/C29H36O15/c1-11-22(32)24(34)26(36)28(41-11)40-10-20-23(33)25(35)27(37)29(44-20)42-13-7-14(30)21-15(31)9-17(43-19(21)8-13)12-4-5-16(38-2)18(6-12)39-3/h4-8,11,17,20,22-30,32-37H,9-10H2,1-3H3/t11-,17-,20+,22-,23+,24+,25-,26+,27+,28+,29+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Methyl-Hesperidin is a vasodilating agent[1].|Product information|CAS Number: 11013-97-1|Molecular Weight: 624.59|Formula: C29H36O15|Chemical Name: (2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2H-1-benzopyran-4-one|Smiles: C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=CC(O)=C4C(=O)C[C@H](OC4=C3)C3=CC(OC)=C(C=C3)OC)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O|InChiKey: GUMSHIGGVOJLBP-SLRPQMTOSA-N|InChi: InChI=1S/C29H36O15/c1-11-22(32)24(34)26(36)28(41-11)40-10-20-23(33)25(35)27(37)29(44-20)42-13-7-14(30)21-15(31)9-17(43-19(21)8-13)12-4-5-16(38-2)18(6-12)39-3/h4-8,11,17,20,22-30,32-37H,9-10H2,1-3H3/t11-,17-,20+,22-,23+,24+,25-,26+,27+,28+,29+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 100 mg/mL(160.1 mM). Water: 100 mg/mL(160.1 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.{{Polyethylenimine} medchemexpress|{Polyethylenimine} {Biochemical Assay Reagents}|{Polyethylenimine} Purity & Documentation|{Polyethylenimine} Data Sheet|{Polyethylenimine} custom synthesis|{Polyethylenimine} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Etokimab} site|{Etokimab} Immunology/Inflammation|{Etokimab} Biological Activity|{Etokimab} Purity|{Etokimab} custom synthesis|{Etokimab} Autophagy} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits.PMID:24025603 Its aglycone form is called hesperetin. Hesperidin and methyl hesperidin reduce TNF-alpha-induced VCAM-1 expression through inhibiting the phosphorylation of Akt and PKC. Methyl hesperidin can bind to buman serum albumin (BSA) with binding constants between 18 and 34 mM/L. Long-term carcinogenicity study demonstrates that methyl hesperidin shows no carcinogenicity for B6C3F1 mice in the 96-wk feeding regimen.|References:|Kurata Y, et al. Food Chem Toxicol, 1990, 28(9), 613-618.Li J, et al. Spectrochim Acta A Mol Biomol Spectrosc, 2013, 102, 200-204.Nizamutdinova IT, et al. Int Immunopharmacol, 2008, 8(5), 670-678.Products are for research use only. Not for human use.|