Product Name :
WH-10417-099
Description:
WH-10417-099 is a degrader that could collectively induce degradation of the largest number of unique kinases (>125 unique kinases).
CAS:
Molecular Weight:
1039.16
Formula:
C52H62N8O13S
Chemical Name:
Smiles :
NC1=NC=C(C=C1C1=CC2CCNC(=O)C=2C=C1)C1C=CC(=CC=1)S(=O)(=O)N(CCCNC(=O)CCOCCOCCOCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O)C1CC1
InChiKey:
FBFSEQRYZRBYLH-UHFFFAOYSA-N
InChi :
InChI=1S/C52H62N8O13S/c53-48-42(35-7-12-40-36(31-35)15-18-56-49(40)63)32-37(33-57-48)34-5-10-39(11-6-34)74(67,68)59(38-8-9-38)20-2-17-55-45(61)16-21-69-23-25-71-27-29-73-30-28-72-26-24-70-22-19-54-43-4-1-3-41-47(43)52(66)60(51(41)65)44-13-14-46(62)58-50(44)64/h1,3-7,10-12,31-33,38,44,54H,2,8-9,13-30H2,(H2,53,57)(H,55,61)(H,56,63)(H,58,62,64)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
WH-10417-099 is a degrader that could collectively induce degradation of the largest number of unique kinases (>125 unique kinases).|Product information|Molecular Weight: 1039.16|Formula: C52H62N8O13S|Smiles: NC1=NC=C(C=C1C1=CC2CCNC(=O)C=2C=C1)C1C=CC(=CC=1)S(=O)(=O)N(CCCNC(=O)CCOCCOCCOCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O)C1CC1|InChiKey: FBFSEQRYZRBYLH-UHFFFAOYSA-N|InChi: InChI=1S/C52H62N8O13S/c53-48-42(35-7-12-40-36(31-35)15-18-56-49(40)63)32-37(33-57-48)34-5-10-39(11-6-34)74(67,68)59(38-8-9-38)20-2-17-55-45(61)16-21-69-23-25-71-27-29-73-30-28-72-26-24-70-22-19-54-43-4-1-3-41-47(43)52(66)60(51(41)65)44-13-14-46(62)58-50(44)64/h1,3-7,10-12,31-33,38,44,54H,2,8-9,13-30H2,(H2,53,57)(H,55,61)(H,56,63)(H,58,62,64)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Trilaciclib} site|{Trilaciclib} Cell Cycle/DNA Damage|{Trilaciclib} Biological Activity|{Trilaciclib} In stock|{Trilaciclib} custom synthesis|{Trilaciclib} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Tivozanib} MedChemExpress|{Tivozanib} VEGFR|{Tivozanib} Biological Activity|{Tivozanib} In Vitro|{Tivozanib} supplier|{Tivozanib} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23983589 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:| Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183(6):1714-1731.e10. Products are for research use only. Not for human use.|
