Product Name :
TCMDC-125457
Description:
TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
CAS:
872113-12-7
Molecular Weight:
399.83
Formula:
C19H18ClN5O3
Chemical Name:
N-(5-chloro-2-methoxyphenyl)-2-[N-methyl-1-(2-phenyl-2H-1, 2, 3-triazol-4-yl)formamido]acetamide
Smiles :
CN(CC(=O)NC1=CC(Cl)=CC=C1OC)C(=O)C1C=NN(N=1)C1C=CC=CC=1
InChiKey:
RHRZUZMCICRKJA-UHFFFAOYSA-N
InChi :
InChI=1S/C19H18ClN5O3/c1-24(12-18(26)22-15-10-13(20)8-9-17(15)28-2)19(27)16-11-21-25(23-16)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,22,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.|Product information|CAS Number: 872113-12-7|Molecular Weight: 399.83|Formula: C19H18ClN5O3|Chemical Name: N-(5-chloro-2-methoxyphenyl)-2-[N-methyl-1-(2-phenyl-2H-1, 2, 3-triazol-4-yl)formamido]acetamide|Smiles: CN(CC(=O)NC1=CC(Cl)=CC=C1OC)C(=O)C1C=NN(N=1)C1C=CC=CC=1|InChiKey: RHRZUZMCICRKJA-UHFFFAOYSA-N|InChi: InChI=1S/C19H18ClN5O3/c1-24(12-18(26)22-15-10-13(20)8-9-17(15)28-2)19(27)16-11-21-25(23-16)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3,(H,22,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Transglutaminase} medchemexpress|{Transglutaminase} Purity & Documentation|{Transglutaminase} Data Sheet|{Transglutaminase} manufacturer|{Transglutaminase} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Zoliflodacin} medchemexpress|{Zoliflodacin} Anti-infection|{Zoliflodacin} Protocol|{Zoliflodacin} References|{Zoliflodacin} custom synthesis|{Zoliflodacin} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:34645436 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Chia W, et al. High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics. ACS Chem Biol. 2021 Nov 19;16(11):2348-2372. Products are for research use only. Not for human use.|
