Product Name :
GGTI-286
Description:
GGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s = 2 and >30 μM, respectively).
CAS:
171744-11-9
Molecular Weight:
429.58
Formula:
C23H31N3O3S
Chemical Name:
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylpentanoate
Smiles :
CC(C)C[C@H](NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS)C(=O)OC
InChiKey:
IENQPUVVSDIXCT-UTKZUKDTSA-N
InChi :
InChI=1S/C23H31N3O3S/c1-15(2)11-21(23(28)29-3)26-22(27)19-10-9-18(25-13-17(24)14-30)12-20(19)16-7-5-4-6-8-16/h4-10,12,15,17,21,25,30H,11,13-14,24H2,1-3H3,(H,26,27)/t17-,21+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tusamitamab} MedChemExpress|{Tusamitamab} Protocol|{Tusamitamab} In Vitro|{Tusamitamab} manufacturer|{Tusamitamab} Cancer}
Shelf Life:
≥12 months if stored properly.{{Vobramitamab} web|{Vobramitamab} ADC Antibody|{Vobramitamab} Biological Activity|{Vobramitamab} In Vivo|{Vobramitamab} supplier|{Vobramitamab} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:22664133
Additional information:
GGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s = 2 and >30 μM, respectively).|Product information|CAS Number: 171744-11-9|Molecular Weight: 429.58|Formula: C23H31N3O3S|Chemical Name: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylpentanoate|Smiles: CC(C)C[C@H](NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS)C(=O)OC|InChiKey: IENQPUVVSDIXCT-UTKZUKDTSA-N|InChi: InChI=1S/C23H31N3O3S/c1-15(2)11-21(23(28)29-3)26-22(27)19-10-9-18(25-13-17(24)14-30)12-20(19)16-7-5-4-6-8-16/h4-10,12,15,17,21,25,30H,11,13-14,24H2,1-3H3,(H,26,27)/t17-,21+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
