Mented at 400 mg/kg had constructive effects on growth Metolazone-d7 Metabolic Enzyme/Protease efficiency and diarrhea incidence, specifically in LW weaned piglets.Author Contributions: Conceptualization, X.J.; methodology, X.L. and X.J.; computer software, X.Z.; validation, V.B., X.L. and X.J.; formal evaluation, X.Z. and G.G.; investigation, J.W.; resources, C.C.; information curation, J.W.; writing–original draft preparation, X.Z.; writing–review and editing, M.S. and X.J.; visualization, X.L.; supervision, X.J.; project administration, V.B. and X.J.; funding acquisition, X.J. All authors have study and agreed for the published version of your manuscript. Funding: This study was funded by the Central Public-interest Scientific Institution Basal Study Fund (1610382021012) plus the Intergovernmental International Science, Technologies and Innovation Cooperation Important Project on the National Essential R D Program (2018YFE0111800). Institutional Critique Board Statement: The study was performed in accordance with the recommendations in the Declaration of Helsinki, and authorized by the Institutional Evaluation Board (or Ethics Committee) in the Animal Care and Use Committee of Institute of Feed Study with the Chinese Academy of Agricultural Sciences (protocol code FRI-CAAS-20200815 and date of approval is 15 August 2020). Informed Consent Statement: Not applicable. Data Availability Statement: The data presented within this study are Moexiprilat-d5 supplier obtainable on request from the corresponding author. Acknowledgments: The authors gratefully appreciate the financial help supplied by the Central Public-interest Scientific Institution Basal Investigation Fund (1610382021012) plus the Intergovernmental International Science, Technologies and Innovation Cooperation Important Project with the National Crucial R D Plan (2018YFE0111800). Conflicts of Interest: The authors report no conflict of interest. The authors are solely accountable for the content material and writing of this short article.International Journal ofMolecular SciencesReviewA Short History and Future Prospects of CEST MRI in Clinical Non-Brain Tumor ImagingTianxin Gao 1 , Chuyue Zou 1 , Yifan Li 2 , Zhenqi Jiang 1 , Xiaoying Tang 1, and Xiaolei Song 2, College of Life Science, Institute of Engineering Medicine, Beijing Institute of Technologies, Beijing 100081, China; [email protected] (T.G.); zou15211137@163 (C.Z.); [email protected] (Z.J.) Center for Biomedical Imaging Research, College of Medicine, Tsinghua University, Beijing 100084, China; [email protected] Correspondence: [email protected] (X.T.); [email protected] (X.S.)Citation: Gao, T.; Zou, C.; Li, Y.; Jiang, Z.; Tang, X.; Song, X. A Brief History and Future Prospects of CEST MRI in Clinical Non-Brain Tumor Imaging. Int. J. Mol. Sci. 2021, 22, 11559. ten.3390/ ijms222111559 Academic Editor: Matteo Landriscina Received: 2 September 2021 Accepted: 23 October 2021 Published: 26 OctoberAbstract: Chemical exchange saturation transfer (CEST) MRI can be a promising molecular imaging tool which makes it possible for the certain detection of metabolites that contain exchangeable amide, amine, and hydroxyl protons. Decades of development have progressed CEST imaging from an initial notion to a clinical imaging tool that is certainly used to assess tumor metabolism. The initial translation efforts involved brain imaging, but this has now progressed to imaging other physique tissues. In this review, we summarize studies employing CEST MRI to image a selection of tumor types, including breast cancer, pelvic tumors, digestive tumors, and lung cancer. Approximately two thirds with the published studi.
