E authors’ know, the pathogen impact was for first time also measured using indicators other than H-index (M quotient, A-index, G-index, HG-index and G/H ratio). Moreover, considering that none of jasp.12117 these indices reflects the particular contribution within the H-index from an author, an institute or a country, a new index “Deciphering Citations Organized by Subject” (Dcos) is proposed. Overall, the results obtained in the present study can be useful to know the hottest topics in swine research. In addition, Dcos scores can be used to evaluate if an author, an institute or a country have a significant impact in a particular research pathogen or topic.Materials and Methods Selection and grouping of pathogensThe present study comprises all known organisms that cause infection/infestation in pigs (from now on, infectious agent or pathogen). The major internationally-recognized reference book in swine veterinary medicine “Disease of swine” [21] was mainly used to construct the final database of pig infectious agents. This database Ixazomib citrate biological activity included the pathogen name, its taxonomic division, the information on whether it had zoonotic potential, if it was emerging or not emerging, and whether it caused an OIE-listed disease or not. Pathogens were defined as non-emerging or emerging if they have been firstly described in pigs before or after the last 20 years, respectively [15] and the grouping into OIE-listed diseases was done according to the information available at the OIE website [22]. The list and grouping were completed using institutional websites from two European projects included in the 7th Framework Programme: the ENHanCEd Infectious Diseases (EID2) [23] and DISCONTOOLS [24]. EID2 is an evidence-based database that uses publicly available databases to compile data on vectors, hosts SART.S23506 and their pathogens. Among other information, it collects data on spatial and temporal distributions of infectious agents and bibliographic and other supporting evidences. The impact of the spatial distribution of pathogens on H-index scores was evaluated by collecting its distribution (worldwide, continental or national) from EID2. The DISCONTOOLS project (Development of the most effective tools to control infectious diseases in animals) aims to be a tool to target research funding and prioritize research. Both EID2 and DISCONTOOLS sources were already used in previous papers analyzing human and domestic animal pathogens in Europe [16], and emerging hazards in North-America [14], according to the H-index scores. Also, other institutional and governmental websites from the Netherlands [25], Australia [26], and the USA [27] and the internationally-recognized reference publication in veterinary medicine The Merck Veterinary Manual [28] as well as Meng [29], were used to Nutlin-3a chiral chemical information complete the list and the grouping of pathogens. Using the abovementioned sources, the H-index was calculated for a total of 137 swine pathogens: Viruses (n = 52), Bacteria (n = 39), and Other (n = 46), in which helminthes, protozoa, external parasites (classes Insecta and Arachnida), and fungi were included. Overall, most of them were considered non-emerging (86.1 ) and/or zoonotic (62.8 ), as summarized in Table 1. In particular, Virus was an exception as majority of the members included in this group were assigned in the Non-zoonotic status (65.8 ). Regarding Emerging group (n = 19; 13.9 ), it was mainly composed by viruses (18 Virus, 1 Bacteria, 0 Other). Finally, only 24 out of 137 (17.5 ) of the.E authors’ know, the pathogen impact was for first time also measured using indicators other than H-index (M quotient, A-index, G-index, HG-index and G/H ratio). Moreover, considering that none of jasp.12117 these indices reflects the particular contribution within the H-index from an author, an institute or a country, a new index “Deciphering Citations Organized by Subject” (Dcos) is proposed. Overall, the results obtained in the present study can be useful to know the hottest topics in swine research. In addition, Dcos scores can be used to evaluate if an author, an institute or a country have a significant impact in a particular research pathogen or topic.Materials and Methods Selection and grouping of pathogensThe present study comprises all known organisms that cause infection/infestation in pigs (from now on, infectious agent or pathogen). The major internationally-recognized reference book in swine veterinary medicine “Disease of swine” [21] was mainly used to construct the final database of pig infectious agents. This database included the pathogen name, its taxonomic division, the information on whether it had zoonotic potential, if it was emerging or not emerging, and whether it caused an OIE-listed disease or not. Pathogens were defined as non-emerging or emerging if they have been firstly described in pigs before or after the last 20 years, respectively [15] and the grouping into OIE-listed diseases was done according to the information available at the OIE website [22]. The list and grouping were completed using institutional websites from two European projects included in the 7th Framework Programme: the ENHanCEd Infectious Diseases (EID2) [23] and DISCONTOOLS [24]. EID2 is an evidence-based database that uses publicly available databases to compile data on vectors, hosts SART.S23506 and their pathogens. Among other information, it collects data on spatial and temporal distributions of infectious agents and bibliographic and other supporting evidences. The impact of the spatial distribution of pathogens on H-index scores was evaluated by collecting its distribution (worldwide, continental or national) from EID2. The DISCONTOOLS project (Development of the most effective tools to control infectious diseases in animals) aims to be a tool to target research funding and prioritize research. Both EID2 and DISCONTOOLS sources were already used in previous papers analyzing human and domestic animal pathogens in Europe [16], and emerging hazards in North-America [14], according to the H-index scores. Also, other institutional and governmental websites from the Netherlands [25], Australia [26], and the USA [27] and the internationally-recognized reference publication in veterinary medicine The Merck Veterinary Manual [28] as well as Meng [29], were used to complete the list and the grouping of pathogens. Using the abovementioned sources, the H-index was calculated for a total of 137 swine pathogens: Viruses (n = 52), Bacteria (n = 39), and Other (n = 46), in which helminthes, protozoa, external parasites (classes Insecta and Arachnida), and fungi were included. Overall, most of them were considered non-emerging (86.1 ) and/or zoonotic (62.8 ), as summarized in Table 1. In particular, Virus was an exception as majority of the members included in this group were assigned in the Non-zoonotic status (65.8 ). Regarding Emerging group (n = 19; 13.9 ), it was mainly composed by viruses (18 Virus, 1 Bacteria, 0 Other). Finally, only 24 out of 137 (17.5 ) of the.